[sdedovic]

> the search for small molecule drugs building on this observation seems to have been fruitless

I imagine this is such a perfect use case for large-scale data analytics. Maybe with the next (or n+2 or n+10) generation of wearables we may be able to track some of the macro effects of diet, exercise, air quality, sleep, etc. at such a big scale that we can determine how individual factors can affect mood and behaviour.

Ignoring the privacy and political concerns aside, it seems like such a cool problem space.

[doingtheiroming]

One of the challenges faced in the early days was simply to get the bacteria to reproduce. It’s not clear for any given bacteria what substrate and food source is useful. Not being able to do that was an obstacle to the analytics since much of the basic data couldn’t be developed. It seems we are better at that now.