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by DrBoring
1526 days ago
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> I suspect depression medications may inhibit the effect? When I was on Wellbutrin, it stopped the mental effect of alcohol. When I imbibed, there was no loss of inhibition normally associated with alcohol use. However, I did still lose physical coordination. Zoloft did not have the same effect. The brain is a crazy thing. |
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In general I think this is most pronounced even within antidepressants of the same class, with similar binding affinities, some people report limited success with one or the other seemingly similar drug.
All this said, wellbutrin is a very different drug than zoloft. It have more dopamine and norepinephrine activity iirc.
Also for anyone else, try to avoid alchohol and wellbutrin or take it knowing that your seizure threshold goes down on wellbutrin so its easy to black out and do worse than you realize (also related to the reported effects above)