[tbalsam]

A hybrid approach is occasional infusions plus at home. I was infusion exclusive for a while and am at home exclusive now (extremely disciplined about it). But my Ket admin doctor and I both I think have the opinion that the occasional IV treatments.... It's hard to beat.

It just does something different. But then at home can help maintain in a more muted way. I think it's because a mainline infusion has no top end limit for drip speed, whereas buccal/nasal membranes can only transport so much at a time. There's a few dose charts that basically flatline at the beginning as transport/transporter stuff saturates vs the line which goes sky-high. Also the bioavailability is phenomenal, and it's easier with IV to avoid the dose creep/tolerance/psychological addiction aspects.

That said, IV Ketamine is hella expensive. :'( An $80 Ketamine nasal spray (not even with insurance, just that), can last me for 6 months with weekly lower dose solid session topup treatments. So, ~$12 a month. Less than HBO Max w/o ads. Hell yeah. That's a good price for an effective treatment haha. Both seem to have unique benefits too that I haven't easily gotten wjfb the other.

Just a few thoughts but am sure you're on a similar wavelength too so mostly just sharing! Curious to hear what your thoughts experiences were/are/have been.