[physicsguy]

Gonna depend a huge amount on what you're doing to be honest. I used it for physics modelling codes and it made a bit of a difference (comparable to Numba) but dropping to C for the main computation routines was what we ended up doing, and that worked very well for us.

It's very fast to write for, that's the main benefit. Use it together with profiling and just pick off the slowest part first.