[umvi]

Any reason L-glucose could cause cancer compared to R-glucose? I know it's incredibly hard to isolate and distill L-glucose, but to me that seems like the ideal artificial sweetener because it's chemically the same as natural glucose, just with a different geometry that prevents it from being metabolized.

[philg_jr]

According to a reference to a NASA article on the Wikipedia page for L-glucose, it was too expensive to make in large quantities.

[manmal]

Allulose seems to work fine for many, and is widely available.