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by intenex
1560 days ago
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The truly amazing thing here is how powerful the placebo control was, even despite the fact that as someone who's done ketamine IV treatment before, it's pretty obvious when you're on ketamine and when you're not. "At week 6, remission in the ketamine arm remained high, although non-significantly versus placebo (69.5% v 56.3%; odds ratio 0.8 (95% confidence interval 0.3 to 2.5), P=0.7)." |
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1. The "placebo" received standard treatment for suicidal ideation.
2. We should expect a natural regression towards the mean. The vast majority of humans do not experience suicidal ideation in a particular day. People with suicidal ideation tend to move towards the standard human experience of not having suicidal ideation over time.