[thecolorblue]

I have also worked with bioreactors. Sounds like you have made some great progress. Just a couple thoughts:

1) there are plenty of other niches for microbe production that could possibly use the same technology. I am not suggesting you switch now, but something to keep in mind for the future. In my opinion, the current standard processes for working with bioreactors are slow and manual. I think there is a lot of room for efficiency improvements but it is rarely worth it for individual companies to make those investments.

2) Is all of the growth happening in a single bioreactor or do you have multiple sized bioreactors for different stages? I don't have a scientific background and I'm trying to understand the standard practices better.

edit: fixed typos.

[vpribble]

We definitely agree with you that the reactors currently used in biopharma were not really meant for the level of production required to scale cultivated meat. As for the growth, typically you'll find what's called a "seed train" for growing cultivated meat. This is basically a series of reactors starting from a small flask around 10 mL and ending in a reactor greater than 20000L! The train might have reactors along the way, 10mL, 200mL, 4L, 80L, etc. until the final reactor volume is reached. Some of these reactors, especially the larger reactors near the end of the process, are meant to handle the cells at a specific stage in the lifecycle, such as maturing, where the cells grow in volume.

[thecolorblue]

Ah, got it. It is an interesting detail of the process that I would have never thought of coming into the industry.

Thanks for the explanation.

[ada1981]

Can you share more about your ideas?

[thecolorblue]

Which ideas do you mean? 1 or 2?

I realize now that I probably should have made two comments.