[jamesfmilne]

I believe macOS on Apple Silicon or Intel does not support DisplayPort MST (Multi-Stream Transport) which is required for daisy-chaining to work.

[jsjohnst]

MacOS supports MST mirror (which imho is mostly useless outside niche uses), but not MST extend.

[tolle]

Over Thunderbolt at least. I imagine it might subpar on non supported stuff.

[jsjohnst]

Not sure what you mean, Thunderbolt is unrelated to MST.

MST mirroring works with all the MST capable DP monitors I’ve tried (half dozen or so), but have never got MST extend to work.