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by CoastalCoder 1583 days ago
I was a little surprised that the researcher talked only about stopping disease progression, rather than reversal.

Especially for the 7-month old. I assumed that at that age, the brain was still growing / adapting in ways that could work around the earlier problems.

But now that I think about it, I've heard that oxygen deprivation during birth can cause permanent impairment.

2 comments

For genetic conditions like this one, it's typically a positive feedback loop -- aka vicious cycle -- where the sicker they get, the sicker they get and it accelerates.

Stopping the normal progression would be a huge win in its own right.

Reading the article, I'm not seeing much info on how the results were 7 months old in terms of brain development. At that age, one would expect brain development to improve. I hope the researchers discuss this in more detail in future news.