[lorenzfx]

The PI was also involved in an earlier study [1, 2], that found "Jennifer Aniston neurons", i.e., neurons that get activated when the proband gets shown an image of Jennifer Aniston, but not activated when shown the image of another celebrity.

It's probably not that surprising, that other cells are active during other specific activities and inactive during others.

Anyway, it's fun seeing my old institute featured on hn.

  [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210637/
  [2] https://sci-hub.st/https://doi.apa.org/doiLanding?doi=10.1037%2F0033-295X.117.1.297

[amelius]

How precise can this technique determine which neurons fire? Are we really talking about individual neurons, or more about large groups of neurons?

[wallscratch]

There are a few techniques:

Patch clamp recording: you are literally sticking a needle into a single neuron and measuring it’s activity

EEG/MEG: using electrodes to measure activations of many thousands or millions of cells

[bayesian_horse]

I'd rule out patch clamp. That would be too difficult and slow.

It sounds like they have very sensitive electrodes that are either very close to individual neurons, and then they shift those around, or they have a lot of those sensitive electrodes and compute the location of signal sources in 3D space. The latter would be a lot more economical.

[amelius]

Ok, but I guess that recording which neurons fire when the subject is performing certain tasks does not fall into the category of "sticking a needle into a single neuron".

[momenti]

PI?

[lorenzfx]

Sorry.

Principal Investigator See https://en.m.wikipedia.org/wiki/Principal_investigator