Hacker News new | ask | show | jobs
by xiphias2 1586 days ago
What is the main reason that inhaled vaccines are not in use today for flu for example? Is there some new technological breakthrough for delivery that was needed?
3 comments

They are! Inhaled flu vaccines are generally live attenuated virus, which isn't recommended for everyone but is perfectly effective for a large segment of the population:

https://www.cdc.gov/flu/prevent/nasalspray.htm

Nasal flu vaccines are widely used. For example in the UK, all children in school are offered a nasal flu vaccine every year [1].

[1] https://www.nhs.uk/conditions/vaccinations/child-flu-vaccine...

From a lay person's point of view, I am trying to imagine if there would be significant extra mass required to distribute a billion inhalable vs injectable vaccines. It seems like there would be additional mass and volume. Could that be one reason?