[wavegeek]

These symptoms can also he a manifestation of histamine intolerance. If your enzymes that break down histamines (diamine oxidase - DAO or histamine methyltransferase - HMT) are faulty it will be a problem.

High histamines give me the opposite of the effect of taking anti-histamines, which normally make you drowsy.

You would be amazed how many foods are high in histamines. Basically anything that is really flavoursome. And many additives either inhibit histamine breakdown or promote release from the mast cells.

Not to mention MCAS mast cell activation syndrome.

[FollowingTheDao]

Yes histamine, but I need to correct some of what you said. It is common people think diamine oxidase break down histamine because the Amiloride-sensitive amine oxidase (AOC1) used to be called DAO in the genetic research.

https://www.uniprot.org/uniprot/P19801

D-amino-acid oxidase (DAO) is different. https://www.uniprot.org/uniprot/P14920

And the other gene is HNMT (Histamine N-methyltransferase).

I have never had histamine issues, but just to not that most ant-psychotics work on the H1 receptor and they never worked for me.