[wdwvt1]

I think it's really hard - we don't know what a healthy state of the microbiome is. There is likely a lot of individuality, what is healthy for me is maybe not healthy for you. This probably has to do with early life immune system development and what we were exposed to as kids.

At a high level we know that diversity of microbial species in the gut (but for instance, not in the vagina) is linked to better overall health state. Is this because of the microbes? Probably not, it's probably that the microbes are a sensor/responding to an overall healthy diet/ecosystem.

In general, there are commercial services to track your microbiome and they are interesting from a data perspective, but I am not sure you will get much health information out of them.

We know the answer to a healthy diet - there are no microbial talismans - but it's just not sexy. Eat lots of plants, less sugar, and exercise. I wish it was as easy to follow this advice as it is to write haha.

[Jare]

Wonder what evolutionary mechanisms made us (in general) enjoy food that's bad for us a lot more than the one that's good.

[throwamon]

How about the mainstream explanation? Energy used to be scarce, so high-energy foods tasted good. Now we have plenty of energy-dense and tasty food-like stuff without the actual nutritional content.