I have some odd GI issues so there's a clear impact there. The alternative treatment is some very nasty medication. Effective probiotics restore normality without the side effects the medications have. I'll spare you the details ;)
More anecdotally I do feel generally better even when my GI symptoms aren't present: more energy, better mood, more restful sleep.
But how do you know if they're effective?
That's always been my question.
What is the effect one should notice?