[thehappypm]

Still, this is not the primary pathway the virus uses. A Paxlovid resistant virus won’t suddenly have a general evolutionary advantage for growth. It’ll just be more likely to kill people.

[ceejayoz]

Why would a virus that can survive Paxlovid and continue infecting people not have an evolutionary advantage in a society with widely available Paxlovid treatments?

[thehappypm]

There’s clearly an advantage, but I think it’s pretty minimal. Evading immunity or being more contagious would be a much larger increase in fitness.