[ncmncm]

We have pretty good reasons to believe that CBD, in the absence of THC, is protective for people who have contracted COVID: it keeps them out of ICU.

Unfortunately almost all retail products that claim to have CBD don't. CBD from the pharmacy, which does, costs more than people usually want to pay.

[lambdaba]

Are you sure about that? I've bought CBD isolate several times from (decently vetted) online vendors... pretty sure it was pure CBD

Still, pretty amazing CBD would "block" entry of the virus in cells, or something like that (I only read the headlines, not pretending to understand)... But maybe this is somehow how Ivermectin can have antiviral properties at normal doses too. I suppose CBD once the infection sets in is less effective (though surely harmless).

[ncmncm]

How did you verify it was pure CBD? Do you have equipment that would enable such verification? Seeming to have the effect you expect from CBD is not reliable.

CBD's effect on COVID-19 is to suppress the over-reaction of the immune system causing congestion and breathing problems. It does not interfere with the viral life cycle. So, it is useless to prevent COVID-19 infection.

In vitro analysis suggested that, in principle, ivermectin ought to help block COVID-19 virus in several ways. That generated interest to see if it would help.

The more reliable each study has been, the less effect it has shown. Something working great in test tubes (and even in mice) and failing when prescribed to actual people is totally unsurprising to anybody who works in medical research. Something promising that actually turns out to work clinically is always astonishing.

So, discounting promotion by people do lack long experience interpreting medical research results is not corrupt SUPPRESSION OF THE TRUTH. It is simple honest reporting, is doing you a favor, and you should welcome it.

[lambdaba]

I vaped it. It all evaporated every time. And I've tried multiple vendors, I know how the powder looks like, are you suggesting there's a cutting agent or what? Why would a reputable company do that? It's not a very reasonable position. I'm sure there are fakes out there, but not very many, I would estimate.

[ncmncm]

You estimate wrong, then.

Typical preparations, most especially those sold for vaping, turn out on examination to have ~2% of the amount of CBD advertised, where they have any. I.e., they have just enough that a crude test of presence shows something present.

[dekhn]

Actually, here's what I see on a typical vaping prep, for THC but not CBD: TOT THC: 80.94%. Tot THC: 809.42mg. Tot CBD: 0.00mg. The CBD ones typically have between 65% and 99% CBD. Each container has a traceability mark and these things are tested in-house with calibrated equipment.

That said, I buy from a premium dispensary and I have no idea what's vended in smoke shops.

[lambdaba]

I buy pure cbd isolate, powdered cbd. Not a preparation and not sold for vaping. When you've tasted pure cbd you know how to recognize it.

[ncmncm]

Anyway, in answer to your question on whether I am sure CBD helps: No.

I read one good-quality paper that reported an effect, and suggested plausible mechanisms. But the authors cautioned it needed more work before it could be recommended clinically. In particular, there was no hint it might prevent infection, or be useful to treat mild cases. The perhaps surprising bit was that THC interfered with the effect of the CBD.

The US NIH says that fluvoxamine is useful to treat serious cases. Any doctor can prescribe that.