[drekk]

my favorite part about your response here is how you didn't answer any of the questions and gave a hand-wavey response about how they're wrong.

[dnautics]

alright, do you want a specific answer? My guess is it's somewhere around one in 3^{5-6}-ish, for the singular founder event that establishes and fixes that sequence as the canonical sequence for the furin cleavage site of COVID-19.