[clomond]

Can't say that 'it is the end' yet - but given that pandemics end when there is no more 'room' for the virus to move through naive hosts (places to infect). The fact that Omicron is SO contagious means it will effectively find any pockets of 'fuel' in the adult human population in the coming weeks and months. Everyone will be exposed.

It is probably more accurate to say it is the likely start of the transition between 'pandemic' and 'endemic' phase. We say endemic as it LOOKS like the gap between coronavirus immunity length to viral instability (number of changes) is longer than for influenza. (T-cell response still very strong, original SARS patients almost 2 decades later have cross immunity to SARS-Cov-2, Omicron immunity effective against delta, etc) That said - it is VERY unlikely to be eradicable at this point due to its ability to infect so many different species and circulate and breed in the wild (more so than even influenza).

So new variants down the line in the coming years/decades is more likely (not different than swine flu, bird flu, etc pandemic risks in the recent past). But, if longer term immunity holds up - none of these will have anywhere near the impact given the absence of billions of naive hosts to burn through.

So if we call the transition from pandemic to endemic the end (likely, yes) - then probably.