| Myocarditis. I know several mothers squeamish on risking their children to continual rolling of the dice w.r.t the mRNA vector vaccines. Also, I can unequivocally state that no other vaccine have I ever seen that has to be continually boosted to maintain it's efficacy, which sounds to me like a deficiency in memory cell formation. The bigger issue there, is that in spite of that being an interesting quirk of these vaccines to do research on, no one will, because having "this year's model" of vaccine is a jackpot to Pharmaceutical companies. Dat Annual Recurring Revenue producing nothing but upsides for them. -New repeatably, and reliably recurring business
-Relaxed or increasingly streamlined approval processes to be lobbied for the next time they want to sneak something through And the downsides being safely (to them) externalizable -increased attrition of horseshoe crab populations and concomitant environmental knock-on effects
-accumulating social costs in the damage done by implementing the infrastructure for implementing things like vaccine passports, which can be adapted to non-public health use cases. I mean, I get where you're coming from. However, I've researched the supply chains, and the stuff that is relied upon for QC'ing this stuff (horseshoe crab blood) is not inexhaustible, and the incentives we're manufacturing are not at all ideal. Just because you've stopped analyzing the problem at the physiological effects on the patient does not mean there isn't reason for concern. Everything is interconnected. |
The mRNA vaccines don't produce IgA-mediated sterilizing mucosal immunity and they would not have been expected to, and they should never have really been expected to or promoted as providing sterilizing immunity.
The point, though, is to prevent severe disease and death which is mediated through memory cells, which are doing just fine and not waning, and mostly likely responsible for the bulk of the headlines that Omicron is less virulent -- because the vaccines are actually working for their intended purpose (turning severe COVID into a bad cold).
The vaccine misinformation on HN is really crazy. Conflating lack of protection against infection to failure to form memory cells is not a remotely well informed take.
The DYOR crowd does the absolute worst research. I don't have a problem with the policy in the title article because you all don't know what you're talking about.
And a multiple shot series of a vaccine is common, most of them are. The initial interval with the mRNA vaccines was probably too short for hypermutation/maturation to happen (but was necessary to get people protected as fast as possible, and to keep the trials as short as possible) so the "boosters" are the really the second shot of a two shot series.