Hacker News new | ask | show | jobs
by desine 1637 days ago
They very much are interesting, and that's a pretty wild story. There are people a lot smarter than me, doctors in the field, that think we have some of our fundamental understanding of viruses wrong. I haven't read enough to take a stance that 100+ years of research is incorrect, but I do love hearing alternative hypotheses on a variety of topics. I don't think there's any harm in hearing what others have to say, at least.
2 comments

What aspect, specifically, is suspected to be wrong? The scientific understanding of viruses might be further along than most doctors suspect. There are concepts like pangenome that are becoming appreciated at the research level that might not have gotten to doctors yet.
This is completely off topic, and I apologize, but I clicked your profile.

First off, I am impressed by your credentials, very nice work, you should be proud.

But this segment in your about: box is oddly hilarious to me. Maybe I've just had too much champagne. Happy New Year, from a West Coaster posting at 12:05 AM.

>yt code channel: https://www.youtube.com/playlistlist=PLf5mA1y1vDNlydJ8d5CmSt...

>[censored by desine] dot [also censored] at the only useful google service

haha that's a good point. I should change it. This is what happens with incremental changes and no unit tests
>What aspect, specifically, is suspected to be wrong?

That depends on who you ask. Different people have different hypotheses and concepts they explore.

Too late to edit, but I'm getting mixed votes (which I usually don't pay much attention to), so I will explain:

There's a few different frameworks people are working within. From my experience, linking or forwarding to any "outside the box" ideas in this sphere will only invite more downvotes, argumentation over the details, and flamewars. Any linking of these ideas would be interpreted by some to be an endorsement of them. In my parent comment I made sure to mention that none of them were worthy of my endosement at this time, though I do find them interesting. Anyone reading this comment, buried deep in "hacker news" is capable of finding alternative ideas outside the norm. You can do your own research, if you like.

I mentioned them because the idea of people disagreeing on this was actually more foreign to me than "flat earth" which I find "pretty far out there", when I first stumbled upon it. It's very uncommonly discussed, and I don't have the clout to either endorse or properly antagonize these ideas. It's intriguing to me that something as preposterous as "the earth is flat" can be much more widely known and discussed than "maybe the way we frame viruses is incorrect".

I mean I suspect that the flu pangenome was evolving "meta-capabilities" to evade the way that our flu vaccines are selected by the authorities, you can see, vaguely, a declining efficacy of the flu vaccine in the last 5 years pre-pandemic (admittedly this could also be noise, or it could also be a measurement artefact due to better tracking). However, we'll probably never know since the flu patterns totally got rekt these past two years, which means any large-scale evolutionary trends, if they existed, probably, got the reset button pushed on them.
That's rather interesting, and I haven't heard anyone else talk about this. A bit frightening too.
Century old understandings in science have been repeatedly upended, so I could see it happening in virology too. I have my own theories based on my reading. And I've seen your comments frequently and find your perspective refreshing, could I contact in some way? You can reach me at the email in my profile.