[btschaegg]

If I may flip your question around and ignore the technical things you seem to be after:

What certainly won't change is the way humans work. That means that the way they use tools also won't change much (modulo maybe some newly established conventions).

As a direct result, the way Don Norman simplifies the process in figure 2.7[1] of "The Design of Everyday Things" will stay relevant. If you intend to build tools for humans -- even if those tools are digital -- it will be a good idea to keep the principles of feedback and feedforward in mind. If you want to learn timeless skills, it might be a good idea to learn more about your audience (i.e. users) instead of new and shiny technologies.

[1]: https://books.google.ch/books?id=I1o4DgAAQBAJ&pg=PT76&dq=des...