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by daedalus_f
1637 days ago
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That is not how randomised controlled trials in conditions like cancer work. They are almost always a riff on new drug + current best treatment regime vs current best regime. Sometimes a drug within a regime is swapped with the new agent and the two compared in terms of survival and toxicity. Progress in cancer treatment is almost always achieved by incremental tweaking of how we treat it. There are a few revolutionary agents based on specific disease mechanisms in certain cancers (e.g. imatinib [1]) but these are in the minority - cancer is protean. [1] https://en.m.wikipedia.org/wiki/Imatinib |
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