[remram]

NodeJS (V8) is faster than CPython, and NodeJS was built for this precise use case. I wouldn't use it over Python personally though, I don't use NodeJS and would sooner reach for Rust if performance mattered.

Concurrency is an important limitation as you've noticed, but it's already a problem for CPython. You would be able to squeeze out more req/s from NodeJS than CPython, up to a point where you would need to bring in something extra to scale to all the cores of one machine (multiprocessing in Python, something like Cluster in NodeJS) which you wouldn't need in Go/Rust/Java.

Then of course scaling further, you would need a system to run jobs across machines, and your choice of Go over Python wouldn't necessarily matter so much. The difference in performance wouldn't limit what you can do, it would just change what you pay for compute. If your compute costs more but your devs can implement features faster, performance is usually unimportant.