[forgotmyoldname]

Flu shots are “updated” every year for new variants.

I might be wrong, but I think covid boosters so far are all just extra doses of the same old material. I don’t think anyone would get flu shots if we were expected to get 4 doses of the same thing with demonstrated lower efficacy.

I’m perfectly fine with getting boosters if they’re adjusted to be more effective against new strains. Getting a third, fourth, or fifth dose of the same old strain that’s basically been evolutionarily eliminated seems off to me.

[gambiting]

Which is why all of these companies are currently working on "v2" of the vaccine which specifically targets omicron. But since the current version of the vaccine was found the be effective anyway, that's why it's being used. I imagine by the time next year it won't be in use anymore, purely because of its lack of effectivness for whatever variant is around then.

[noir_lord]

I think that is exactly the way we are heading as pandemic becomes endemic.

A yearly shot for vulnerable people possibly rolled in with your flu shot (or at least scheduled the same way).

I go get my flu shot every year since I'm classed as vulnerable for health reasons - the exact same reasons I went and got both covid shots and the booster the second I could.

[maxerickson]

The response to the COVID shots isn't linear, so it doesn't come down to just doing the same thing 3 times.

[whynotminot]

You’re thinking about the booster wrong. Having a vaccine for the ancestral strain is actually pretty great, because it confers (or has to this point) some level of protection against all child strains due to there being at least enough similarity still.

If you make some highly specific omicron booster, it might not do anything against whatever variant comes next.

As long as the original shot keeps working, it’s the best one to ride with for now.

[throwaway894345]

With how much more contagious omicron is, I wonder what the odds are that future strains will come from it or an earlier strain? In particular, I assume there is some zero-sum competition going on between strains—if someone gets infected with Omicron it becomes very unlikely that they would later contract Delta—thus at a certain point Omicron is everywhere and less contagious strains largely die out? This has happened in the past with syphilis, for example.

[whynotminot]

It’s sort of interesting to think about. One epidemiologist I follow mused that we could end up with delta and omicron co-existing, with omicron hitting the vaccinated (but not boosted) while delta continues to wreak havoc among the unvaccinated. It’s hard to tell if omicron is actually more contagious than delta, or if it just appears to be because of its immunity evasion.