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by Turing_Machine 1645 days ago
Tobacco has psychoactive substances besides nicotine.

In particular, it has monoamine oxidase inhibitors, which are effective against depression, panic disorder, and social phobia.

https://en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor

Some believe that this is why replacements that contain only nicotine (e.g. nicotine gum and patches) aren't really all that effective as smoking cessation aids.