I clicked the first
https://guix.gnu.org/en/packages/python-pyxel-1.4.3/
It says "Package source: game-development.scm" linking to https://git.savannah.gnu.org/cgit/guix.git/tree/gnu/packages...
It's a lisp code that does what a shell script might do, but declaratively. Indeed it isn't much different from an Arch Linux PKGBUILD.