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That article strikes me as largely playing a semantic game. From the article: >The classic tale of sterilizing immunity unfolds something like this: A pathogen attempts to infiltrate a body; antibodies, lurking in the vicinity thanks to vaccination or a previous infection, instantly zap it out of existence, so speedily that the microbe can’t even reproduce. No symptoms manifest, and most of the body’s immune cells never get involved, a bit like an intruder smacking up against an electric fence around a building, leaving the security guards inside none the wiser. and >This is a very neat story. And it is “almost impossible to prove,” Mark Slifka, an immunologist and vaccine expert at Oregon Health & Science University, told me. To show sterilizing immunity, researchers have to demonstrate that an infection never occurred—a big ask, considering that microbiologists can’t even agree on what an infection actually is. If that is the definition used, yes, you are right. It is also basically useless as a term, as it is 'almost impossible to prove.' If you wish to use another term, we can do that. Instead of sterilizing, I could simply say 'highly effective.' Suffice to say, the mechanisms used by the COVID vaccine and the polio vaccine are very different. At most, the polio vaccine only included 3 strains (or variants)- the Salk vaccine, the first, only targeted type 1, but two more were added later over the course of years. All of this is to say- the highly effective polio vaccine works because there are very few polio variants and people are immunized against them directly. The COVID vaccine does not make one immune to the virus, or immune to the spike protein. The presence of the spike protein in the vaccine provokes an autoimmune response in the form of antibodies that will target that spike protein. This is somewhat effective, and a clever 'hack' that allows us a measure of protection. However, different spike proteins can be used by different variant viruses. I am not antivaccine, and while autoimmune systems can be fairly complex, it is certainly worth discussing. Frankly I find the obfuscation and sloppy, ideological reporting to be frustrating. On all sides I see a lack of rigor and emotional attempts at control. |
Would someone who is flagging this comment please, instead, respond to it? If it is so trivially dismissed, please show the rest of us.