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I had used IDA+HexRays for a few years between 2009 - 2017 but abandoned it entirely in favor of Binary Ninja and Ghidra (and to a lesser extent Hopper and Radare).

While IDA certainly has the first mover advantage, I've found that Binja and Ghidra in combination are able to achieve full coverage of my targets. If you're just targeting x86, you can probably get away fine with Ghidra. Although I've found for non x86 ISA's, Ghidra and Binja each have better or worse support for certain arch's but the ven diagrams overlap to full coverage.