[Dudemeister_]

You can run the profile manager from the terminal with `firefox --profilemanager` and manage the profiles from there Then you can create separate 'shortcuts' for each profile with this `firefox --profile [path to the profile]`

[foepys]

I have been using this workflow for years now. It separates literally everything: cookies, site settings, window size and position, configuration, add-on settings, etc.

This way I can emulate a fresh profile, a restricted profile with tracking protection, and a completely locked down profile with more or less everything disabled. My private Firefox in completely unaffected by my development profiles and I can open multiple profiles at once, theme them differently, and I know exactly which kind of instance I'm using.

It's excellent and works flawlessly for over a decade now.

[forty]

How do you choose in which profile links from outside of the browser should open?

[Dudemeister_]

This depends on what profile you make the the default startup profile in the profile manager

[forty]

Do you know if there is a way to be prompted each time?

[sp332]

You could find where in your desktop environment it decides which app to open, and replace "firefox" with "firefox --profilemanager".

[case]

If you’re on a Mac, Choosy is a great app for this:

https://www.choosyosx.com/

I have no affiliation with them, just a long-time happy user.