I don't think I overstate the relevance of what Django did by saying that Django almost single handledy advanced the state-of-the-art of web deployment in Python forward a decade.
Zope hails from the era when Python was trying to appeal to programmers by showing that it, too, could be a Serious Enterprise Language. Everything had layer after layer of abstraction and the code looked more like Java than Python. The Zope ORM was kind of nice in its own weird way, though.
Zope had some things like the Language Is The Database trope that sort of remind of the things described in those Bank Python blog posts that have been floating around recently.