If you do not understand why your performance profile is as it is, how do you know next week's patch won't make it perform better on AMD machines suddenly? You should understand your problem before you solve it.
If you know how your application performs and why, you are well equipped for estimating potential impact of patches and hardware. Obviously you still need to profile. In any case complete ignorance should not be the accepted approach.
That being said, it would prepare one to better analyze next week’s patch,