Hacker News new | ask | show | jobs
by marwatk 1661 days ago
Isn't Delta vs Alpha a pretty convincing counter argument? It was more transmissible, more severe and better at avoiding acquired immunity.
2 comments

Source for the Delta variant being more severe? I hadn’t heard that.
Are we certain Delta was/is more severe? Since it’s more contagious, might it also be producing a lot more mild/asymptomatic cases that don’t get reported? Severity seems like a difficult thing to measure reliably if you can’t be sure about the denominator.
Multiple countries have sustained mass testing of at least certain groups of population. The argument about undetected asymptomatic cases would be valid in early 2020 when tests were scarce, but now there are good continuous metrics from people who get tested even if asymptomatic.
Gotcha—I’d be interested in links to some of this research. I wasn’t aware there was conclusive evidence that it’s more severe.
Oh, I'm not following the news on Delta or any other variants much, however, I just know people who are measuring the prevalence of variants in the general population in reasonable ways which would definitely cover also asymptomatic people (one is mass testing - e.g. right now 100% of local kids are getting weekly tests in schools, and all hospital admissions get tested even if it's e.g. a car crash, but there's also the viral analysis in sewer system, which is a cool way to get a total perspective on large populations), so studies about the severity of Delta (whatever they are saying) should not be distorted by the particular problem of asymptomatic cases not getting reported, the researchers now have good tools to get the "denominator" part correct.