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by naasking 1666 days ago
> You're pushing a narrative that spike-only vaccines are worse in the face of mutation, and there's just no evidence of that

"Pushing a narrative" is a pretty uncharitable interpretation of a short off-hand comment.

There actually is some evidence that the infected have a stronger immune protection to exposure than the vaccinated, and there are mechanistic reasons this would make sense, so I wouldn't go so far as there's no evidence for it. We'll just have to wait and see.

1 comments

There's mechanistic reasons why the infected would have weaker immune protection because other viral proteins like ORF8 suppress MHC-I expression and T-cell responses. All the studies that I've seen that look at the problem properly find that recovery from infection provides highly variable protection with younger and less severe symptoms providing much less than vaccination.