[alevskaya]

I specialized in high throughput synthetic biology and in applications adapting vectors and pathogenic proteins to subvert the human immune system (for immunooncology mostly). So I have all the background needed for supervillain thinking here :p Of course you can do multiplex markerless construction - but it’s a huge pain in the ass at these lengths and it still leaves open the question of what the point of such work would be.

I feel like I’m taking crazy beans - 20 years ago a satbecoronavirus from a wet market nearly started a global pandemic - hell my colleagues at the time were the ones that identified it as a coronavirus! We have epidemiological evidence this happened again. Absolutely nothing about this sequence is obviously synthetic or even unusual for coronaviruses. How is zoonosis not the null hypothesis?