[suchow]

You say each letter separately; it’s an acronym and stands for Proceedings of the National Academy of Sciences.

[micromacrofoot]

No matter how you say it, the acronym still sounds a little like "penis," there's no escaping it. I've seen this topic come up organically at least a dozen times.

Which arguably is better than the joke ... "Paper Not Acceptable Science" or "Probably Not Any Science"