I would guess things like how nerves and bones work is more similar across species than, say, how drugs might work on the brain, where a mouse brain is a hell of a lot different to human. Is that a reasonable assumption?
I was wondering the same thing. Pluses and minuses...
Rodents represent readily available models that can be used for a deeper understanding of basic biological mechanisms and for proof of concept for preclinical research hypotheses. However, attempts at direct clinical translation to humans have proven problematic or even impossible to date, principally due to issues of scaling and complexity.
Rodents represent readily available models that can be used for a deeper understanding of basic biological mechanisms and for proof of concept for preclinical research hypotheses. However, attempts at direct clinical translation to humans have proven problematic or even impossible to date, principally due to issues of scaling and complexity.
https://clinmedjournals.org/articles/ijscrt/international-jo...