Mine would be booting into a minimal Linux installation/hypervisor that fires up a Linux and a Windows VM, both full-screen, between which you could swap with a pair of keyboard shortcuts.
reddit r/vfio and the arch wiki page here https://wiki.archlinux.org/title/PCI_passthrough_via_OVMF there's also the level1tech forums which have a ton of information on it. The gist of it is this: Qemu with uefi boot, configured through virt-manager, passing in both the gpu and windows boot disk (nvme) as raw devices to the vm.
I did the same and fixed the license issues by pirating windows.
As for drivers, the idea is that you're passing through as much of the devices as possible so it works on that level. For those you cannot passthrough, Windows 10 was surprisingly accomodating.