[ketzo]

I mean, this is purely anecdotal, but if I drink two or three glasses of wine in a night, I get noticeably worse sleep quality than if I drink nothing.

There are long-term effects associated with heavy drinking, but there are also short-term negative effects (for some people) associated with pretty much any alcohol consumption at all. Headaches, acid reflux, etc.

[wing-_-nuts]

Yep, some people are especially sensitive to alcohol, and it does absolutely trash one's rem sleep. This is why I typically only drink on the weekends, limit consumption, and try not to drink after 4-5pm.