[warech]

This is a link to the full text: http://extremelongevity.net/wp-content/uploads/als_discovery...

I'm hesitant to put too much hope in this discovery. I would expect a discovery of this magnitude to be published as a full article in Nature, rather than a Nature Letter. I'm not sure of the difference in the publishing process for the two, but Letters generally come across a bit rushed and are less exhaustive than published articles (citation needed).

[avalind]

The difference between letters and full articles is described here [1]. I don't think that one should view the length of the paper or whether it's published as a Letter or an article as a marker for its scientific importance.

For instance, The paper that Watson & Crick published that described the structure of DNA was only slightly longer than a single page [2].

[1] http://www.nature.com/nature/authors/gta/2a_Manuscript_forma... [2] http://www.nature.com/nature/dna50/watsoncrick.pdf