Have there been any publicized studies done on the reliability of aircraft engines, with and without lead? I’m guessing this is what made the transition take so long, but I can’t seem to find any references.
It’s a rather complex topic with all sorts of factors including economics of a small market and FAA red tape. Av web has a great multi part on failure modes of engines and why new engines often don’t succeed
Another problem is, IIRC, that many replacements for leaded fuels have evaporation & performance issues at lower pressures that don't matter in a car but can be critical in airplane (it's even worse with ethanol additives, IIRC).
https://youtu.be/mwpzTnLC8BY
https://youtu.be/_k1TQGK3mZI