[taxyovio]

Be aware that the said antidepressant is an SSRI, which has the potential to cause permanent sexual dysfunction (PSSD) [1]. It seems that we don’t quite understand how the drug works. Most doctors threw this condition out of the window by claiming SD is caused by depression. There have been some recent studies showing possible mechanisms behind it. Some manufacturers and healthcare organisations (NHS) are beginning to label this as a potential side effect. But in general it’s not well known.

[1] https://rxisk.org/post-ssri-sexual-dysfunction-pssd/

[podgaj]

I can tell you from personal use as someone with Bipolar Disorder, my ding-a-ling works fine before I start taking it and after the first week I have nothing but a wet noodle down there. So no, the SD is not caused by depression, it is caused by Prozac.

The mechanism of action how this helps is probably so simple that people who have over complicated thoughts cannot see the answer. Serotonin is made from tryptophan by the TPH enzyme. But Tryprtophan is also turned into kynurenine by an enzyme called IDO. This kynurenine pathway is crucial to resolving inflammation and the IDO enzyme is directly activated by inflammation.

When you take prozac so much serotonin builds up that it starts inhibiting the TPH enzyme and pushes more tryptophan down the kynurenine pathway and resolves inflammation.

Depression in probably most of the cases is an inflammatory disorder, which is why prozac helps some people with depression.

It has been shown that COVID-19 infection results in alterations of the kynurenine pathway. I will make a guess that prozac will end up helping some people but not everyone.