Yes; check my blog post [1] or latest YouTube video [2] for details, but the tldr is 0.4W (80 mA) idle minimum for Zero W, 0.6W (100 mA) idle minimum for Zero W 2.
Zero W goes up to 160 mA at load, while Zero W 2 gets up to 400-500 mA due to the three extra CPU cores.
Another comment says /sys/devices/system/cpu/cpu[0-n]/online doesn't work, but I think you can get pretty far by changing the CPU affinity at the cgroup or process levels (for userspace) and on /proc/irq/default_smp_affinity (for interrupts). There are likely some kernel threads that would still run on the other cores, but this is reasonably close.
In particular, looks like setting CPUAffinity= /etc/systemd/system.conf will set a default for all of userspace that you can override for particular things as desired.
Zero W goes up to 160 mA at load, while Zero W 2 gets up to 400-500 mA due to the three extra CPU cores.
[1] https://www.jeffgeerling.com/blog/2021/look-inside-raspberry...
[2] https://www.youtube.com/watch?v=lKS2ElWQizA