They haven't found original antigenic sin so far. There's a couple links with some data (although I couldn't find a pre-print or published article right now) in this comment: https://news.ycombinator.com/item?id=29005187
Thanks for the links! Note that they are making variant-specific vaccines, not proving that variant-specific vaccines are effective against the target variant, if delivered after the original vaccine.
Side note: I hope we can do better than taking at face value investor press releases by the biopharma corps producing the vaccines.
>Note that they are making variant-specific vaccines, not proving that variant-specific vaccines are effective against the target variant, if delivered after the original vaccine.
You are correct that it isn't proving vaccine efficacy, but it is showing a different set of antibodies created by the variant vaccines that are more effective at neutralizing the targeted variant than the antibody collection created by the original, WT-targeted vaccine.
>Side note: I hope we can do better than taking at face value investor press releases by the biopharma corps producing the vaccines.
I hate science by press release too. I wish I was better at bookmarking the pre-prints and journal articles I find/read, but they'd just be a mess I couldn't find anything in either :|
Side note: I hope we can do better than taking at face value investor press releases by the biopharma corps producing the vaccines.