[capableweb]

Calling C from Python is very different from calling Java code from Clojure. Clojure always runs on it's host (Java/JavaScript), so calling functions via interop usually speeds up everything with zero overhead, compared to calling C code from Python which does introduce overhead.

Everything in Clojure comes from Java, it's unfair to compare it to "performance is coming from C, not Python" as Clojure works differently.

[MillenialMan]

That wasn't really my point. There is still a translation process you have to apply to cross the boundary between immutable and native data structures though, and that has its own overhead.