[Pigalowda]

The headline and article attempts to generalizes findings from a cohort with Borderline personality disorder - which they admit is a big limitation. I’m not sure what made the researchers think sloppy GABA activation (etoh) would help with a personality disorder because I didn’t read their manuscript.

I can’t see how this got past IRB or how they were able to ethically enroll patients. BPD has many psychological manifestations all rolled into one disorder including rage and emotional lability. It’s a mystery to me why alcohol would be a responsible choice here.

Mild/moderate alcohol consumption does often temporarily alleviate anxiety. But it also pushes the concerns to the next day - and that is the positive feedback loop for increasing daily consumption. This leads to worsening health and worsening/chronic psychological issues that are perpetually pushed back by daily consumption.