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I am in the process of learning Clip Studio Paint by doing some October themed dailies. CSP has gotten a strong rep among indie illustrators for its usability and mix of raster and vector functions. The vector tools I think are particularly outstanding - you can build a whole workflow around line art using vector erase(which automatically chops your selection to the nearest intersection). It also has some great conveniences for scene building with poseable 3D mannequins, perspective rulers and an asset store.