I wonder if a lock-in phenomenon could take place at some point in the future, where non-GM varieties become a no-go and the GM ones get very expensive?
GM crops can produce more yield in worse conditions. As the climate changes, humanity will become increasingly dependent on these crops for survival. And yes, at that point we will be locked in, in the same way we are locked into many other technological advances that make our lives possible. However I don’t expect that will ever make the GM crops more expensive than non-GM, since the land that is capable of growing non-GM will only become more of a rare luxury.