Hacker News new | ask | show | jobs
by mdp2021 1708 days ago
About simulation: we do have simulators of brains (to some extent). The main example is the simulation of the C. Elegans. One such simulator is on GitHub at https://github.com/Flowx08/Celegans-simulation

The problem is, well before tackling the human brain - with functional units, wiring, evolutionary rewiring¹, modules, multiform glias and mysteries in general etc. - that of transparency, i.e. already in the C. Elegans you can see complex behaviour in the studied system, but the hard part, that of understanding why and how that structure presents that behaviour, is unachieved. It is still a "black box" like some ANNs. We know the structure of the C. Elegans since 1985, but we still do not know well "why it works, why it works that way": the "scientific problem" of understanding the "natural phenomenon" we found, in order to export that understanding, is still pending.

So: we have simple brains described, they are simulated, and to just look at them will not make you much wiser until you really manage to "crack the code". There is not really an «Hello World» yet. It does not mean your doctoral efforts could not achieve it though!

--

¹ Evolutionary rewiring: the human nervous system is also made by "afterthought" increases which overlapped on pre-existing structures "patching" them, instead of "correcting, reprogramming" them - so one will find a system that may show to be a masterpiece of cleverness but not a masterpiece of planning. In other words, the human brain is something relatively messy, not a clean blueprint.

3 comments

This feels easily related to lack of unified physical theories.

We seem to find structure all over but no idea why it ended up just this way.

My guess is a link between field effects and information coming off cells. Cells emit information instigating a field reaction but only to a certain point as a survival mechanism.

Once an equilibrium is reached the cells radiate new information to inhibit the field effect?

Which makes me wonder if cells not being able to inhibit field effects is related to aging.

I picked the wrong field in college. Math was fun but the kind of abstract that almost feels useless a lot of the time, and biotech really feels like the final frontier anymore.

It seems https://openworm.org/ is another C. Elegans simulation project (in python). Starting with worms is in the direction of HelloWorld!
> https://github.com/Flowx08/Celegans-simulation

Does it have microtubules?

>#define RANDF() (double)rand() / RAND_MAX

Looks like they tested indeterminism, but it's not used in the final version.