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by Cyril_HN 1708 days ago
Never getting COVID is best.

Hybrid immunity is next best (natural + vaccine).

Vaccine is second best for most cohorts, because it comes with fewer side effects and the side effects typically aren't as bad.

Natural immunity is strong, but for most cohorts is more likely to have side effects compared to a vaccine.

Furthermore, the risk of side effects from COVID are lower if you are vaccinated. Therefore, given that breakthrough cases are still possible, I would suggest vaccinating first, then if they get it they get it and at least you get hybrid immunity in an order that is less risky than natural immunity followed by a vaccine.

For children, all of this is murkier. Also, if the likelihood of you catching Covid is low enough, there's absolutely no point getting vaccinated.

2 comments

> Natural immunity is strong, but for most cohorts is more likely to have side effects

That’s a very generous and evenhanded way to say that

Over a long enough timeline, the likelihood of an unvaccinated person catching COVID is essentially 100%.
Over a long enough timeline, the likelihood of both vaccinated and unvaccinated people catching SARS-CoV-2 (the virus) is essentially 100%. Vaccination significantly reduces the risk of severe COVID-19 (the clinical disease) symptoms, at least for a while.

https://www.nature.com/articles/d41586-021-02689-y

We are pretty much in agreement. My point was that the OPs statement that there is no point in getting a vaccine if you are not going to get COVID was nonsense.