This is very interesting. Are there any books you'd recommend on the topic which would explain the directions pharmaceutical science is heading towards to a layman?
I'm not currently aware of a book on the subject, but would also like to read a compilation of the cutting edge. I am relaying what I know from tangentially following advances my peers participate in filtered through my former chemistry+bioinformatics background.
Here is some more info on considerations to be had for near-future breakthroughs in the oral administration route. The key is in preserving the biologic structure long enough for it to reach the intestine where, in contrast to the stomach, it would be able to enter the bloodstream with the aid of agents that enhance permeability.
https://otd.harvard.edu/explore-innovation/technologies/oral...
Edit: The field of cheminformatics is currently utilizing machine learning to help discover novel drugs in the various search spaces, such as that of kinase inhibitors. They have the ability to function in a multi-target regime. That is, there exist drugs that can be effective for several pathologies.
Here is some more info on considerations to be had for near-future breakthroughs in the oral administration route. The key is in preserving the biologic structure long enough for it to reach the intestine where, in contrast to the stomach, it would be able to enter the bloodstream with the aid of agents that enhance permeability. https://otd.harvard.edu/explore-innovation/technologies/oral...
Edit: The field of cheminformatics is currently utilizing machine learning to help discover novel drugs in the various search spaces, such as that of kinase inhibitors. They have the ability to function in a multi-target regime. That is, there exist drugs that can be effective for several pathologies.